PDI uses the much acclaimed PrecisionDeconvolve™ software to acquire DLS batch data and analyze the correlation functions obtained from the data. Incorporated in the software is a proprietary deconvolution algorithm developed and written by MIT professor Aleksey Lomakin. This algorithm is one of the most accurate regularization programs available today for Photon Correlation Spectroscopy. One of the main features of this algorithm is the ability to obtain stable distributions in real time. It can also be used to observe aggregation processes such as the effect of amyloid beta (Abeta) truncations on amyloid fibril nucleation and growth.

http://web.mit.edu/physics/benedek/alz.html




Advanced Photon Detection

         High sensitivity dynamic light scattering batch system unit for the manual determination of molecular size as the hydrodynamic radius (Rh) from 1.5 nm to 1000 nm. Included with the system is a low volume cuvette (minimum 75 uL) is perfect for protein size, aggregate, interaction, and variable condition (e.g. pH, temperature) conformation studies for proteins, antibodies and other biomolecules. Platform includes 100 mW, 810 nm diode laser, 90 degree dynamic light scattering optics, single aperture (17 um) fiber optic cable, our new integrated photon counting module and autocorrelator, PrecisionDeconvolve software, and an installation tutorial CD-ROM.


System Options:
- Dual aperture fiber optics
        - 17 um slit for ultra high sensitivity of proteins Included in the Price
        - 5 um slit for high concentrations, liposomes/virus
         particles and dense nanospheres.
Included in the Price
- Mini-cuvette and adapter for 20 uL minimum Included in the Price
- Micro-cuvette and adapter for 12 uL minimumUpgrade Price $250
- Multitau Correlator for ultra fast correlation functions Upgrade Price $2,500
- High Powered 100 mWlaser upgrade Included in the Price
- Peltier Heating/Cooling upgrade (4–40 degrees Celsius) Included in the Price